This means that the risk of loss and title for such items pass to you upon our delivery to the carrier.Įvasive Studio attempts to be as accurate as possible. Refunds will be issued within three business days after the receipt of goods to the original form of payment.Īll items purchased from Evasive Stuio are made pursuant to a shipment contract. If you send items more than 14 days after the return label is issued, a 20% restocking fee will be deducted from your refund. Once Customer Service issues you a return label, items must be sent back within 14 days. A 20% Restocking Fee will be applied to returns or exchanges no covered by our Terms and Condition & Shipping Policy. Items returned for reasons other than damage or defects will be approved on a case by case basis. Merchandise purchased in our retail store may not be returned or exchanged online. Please return the item(s) in the original box and packaging. You may return your merchandise within 7 days of receiving your order and we will deduct the cost of shipping from your refund. Paint defects on on items are out of our control and are not considered to be damaged/defective. If you receive an item not in the condition advertised please send us photos by e-mail to All claims must be notified within 3 days of receipt of the product. If you would like to return your merchandise from your purchase, we’re here to help! Please allow 1-2 days after placing the order for us to deliver to the mail carrier you have selected. All other sizes and variations will specify if they will include soft protectors in the product description. All standard 4 inch Funko POPs will ship in a 0.50mm premium soft protector. We do our best to select, pack and ship all items with great care.
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Department of Health and Human Services’ Public Health Service and U.S Fish and Wildlife Service say living in the area does not pose any significant risk.Īn EPA Superfund Record of Decision dated Jstated that official radionuclide testing of the plant site following nearly a decade of plant inactivity showed topsoil sample levels safe enough to warrant discontinuation of further sampling. Department of Energy, Colorado Department of Public Health and Environment, U.S. Environmental groups have expressed concern that the radioactive and toxic contaminants from plant operations and accidental releases have not been sufficiently remediated. The location is south of the former site of the Rocky Flats nuclear weapons production facility. Main article: Radioactive contamination from the Rocky Flats Plant Residents within the area can use State Highway 93 to access Golden or Boulder. There are two access points to the Refuge. The Rocky Flats Wildlife Refuge is to the north and shares a borders with part of the community. It is on the north side of Hwy 72 between Hwy 93 and Indiana St. The Candelas community is located in northwest Arvada, CO. Candelas is divided into six subsections from east to west: Parkview, Mountainview, Canyonview, Valleyview, Townview, and Skyview. The development borders the Rocky Flats National Wildlife Refuge all along its northern property line. The Candelas master planned community is within the most north-western quadrant of Arvada in Jefferson County, Colorado. The formal plan was filed with the Jefferson County Recorder on April 21, 2011. Plans exist for commercial development in the future, in the form of two mixed-use commercial spaces, and a town center, comprising some 7.1 million square feet of commerce in the community. The residential portion of the community is developed by Terra Causa Capital and GF Properties Group (a wholly owned subsidiary of the Southern Ute Indian Tribe), with residences built by Century Communities, Richmond American, Ryland Homes, Standard Pacific Homes, Village Homes, and various custom builders. Pour the cooked meat and onions into prepared pan. Grease (I used PAM cooking spray.) a 9-by-13 inch Pyrex (glass) pan. Put the diced onion in skillet over medium heat.Īdd ground beef, and sauté until cooked and onions are translucent. So I supplemented it with a few cut-up slices of 2% fat American cheese.) I only had about 3/4 cup of the reduced fat cheddar in my fridge, (I used Campbell’s Cream of Mushroom Soup, the 98% fat free variety.) :o) Recipe Tater Tot HotdishĢ cans (10.5 ounce each) cream of mushroom soup, or cream of celery soup No, I am not an Ore-Ida paid spokesperson. I recommend using Extra Crispy Tater Tots to top off this recipe. No fancy ingredients needed to prepare Minnesota Hotdish. It is easy to prepare, uses simple ingredients, tastes yummy, and feeds a group. I found it, here, and I share it below, with my comments in parenthesis and clarifications (mostly for myself) in brackets. The recipe for the Minnesota Hotdish served to Fallon is easy to find on the Internet. Wouldn’t this football-shaped ice cream cake be a yummy addition to any Super Bowl LII made the hotdish recipe, below, famous. You can read about that smile-inducing visit here, and watch it here. After sorting through over 15,000 submissions, Fallon chose to visit the Salzer family in Champlin. Planning his first trip to the Gopher State, while attending football’s biggest game of the season, Fallon challenged his Minnesota viewers to send in their entries inviting him over for a home cooked meal. My recipe of choice hails from 2018 and Super Bowl LII /52 in Minneapolis, by way of talk show host Jimmy Fallon. My first attempt at Minnesota Hotdish was yummy,Īlthough, I did not take the time to neatly line up the tater tots in a straight-line,Īs directed. (view some of those here), there are church ladies’ hot dish recipes, there area grandmas’ hot dish recipes, and many, many more. To choose from! There are Minnesota Congressional Minnesota Hotdish recipes Google “ Minnesota Hotdish recipe” and over 400,000 responses pop up! So many recipes Thank you to Maria Bartholdi for permission to share her fun and informative Minnesota Hotdish: A Love Story video!Ĭlick on the picture above, and then click on the white arrowĬlick, here. With that in mind, I have included a special hotdish recipe (below), to counter any hunger pangs that you may encounter while viewing this program. :o).īeware! Watching this program may make you hungry! Maria has graciously allowed me to share her program with all of you, below. This program light-heartedly explains all that you ever wanted to know about Gem of a program called Minnesota Hotdish: A Love Storyfrom Maria Bartholdi. While researching Minnesota Hotdish for this blog post post, I happily came upon a Me, included! Minnesota Hotdish the “Movie” Some consider the crispy layer of crunchy tater tots the star of Minnesota Hot Dish. It was not until I sampled tater tots in Minnesota (a few years ago), in their preferred crusty, crunchy state, that I fully appreciated the epicurean potential of this cylindrical-shaped potato product! Unlike the lackluster, and soft potato bites that I had eaten in the past, the Minnesota variety is prepared with a solid golden brown exterior, surrounding a soft (grated) potato interior. These crunchy golden “barrels” were gobbled up at Psycho Suzi’s, in Minneapolis. Crispy tater tots are often offered as a yummy side at many-a-Minnesota restaurant. Prices are subject to change without notice. A 20% service charge will be added to all treatments, based on the retail price before discounts. Missed appointments will be charged 100% of the service fee. Twenty-four-hour notification is required for all canceled or changed spa and salon appointments, health and fitness services, private sessions and adventure trips to avoid a 50% cancellation fee. Service Charge, Cancellation & Change Policies A natural anti-aging treatment that rejuvenates the skin from head to toe. A warm Vichy shower and an application of stone crop and arnica moisturizer follows. This allows for maximum absorption of the silky gel body wrap packed with stone crop, aloe and powerful actives to deeply hydrate, soothe redness and brighten the look of skin while you are cocooned. This organic wrap begins with a gentle sugar and salt exfoliation infused with comforting stone crop and anti-oxidant rich lemon peel. A delicious scalp massage to wash and condition your hair completed this truly one-of-a-kind experience. A prickly pear sugar scrub is followed by a full body massage under the warm Vichy shower. Our most luxurious full body treatment utilizes the powerful healing and hydrating properties of desert plants to deeply nurture and renew you. Unscented option available.Ī Sagestone Signature Treatment. A warm Vichy shower rinks and light massage application of rich body butter leaves your skin revived and glowing. This full body exfoliation softens the skin and cleanses the aura leaving you refreshed inside and out, drenched with the aromas of desert sage, lavender and spearmint. A warm Vichy shower rinse and application of a richly moisturizing body silk with the scent of vetiver, sandalwood and jasmine complete the treatment. A scalp massage is performed as the herbs reduce inflammation, balance the body and support the immune system. Whether to calm the nervous system, enliven the senses or balance the body’s energy, you will return to your day feeling profoundly and magnificently different.ĥ0 Minutes, $140 with 25 Minute Massage, $190Ī nourishing herbal blend that provides gentle exfoliation, purification and skin soothing properties with yogurt, honey, ashwagandha, fennel, rosebud and amalaka herbs. Each of our rituals is inspired and intended for very specific purposes. At Sagestone Spa & Salon, the body is a gateway to healing on all levels. All of the photographs on the site are free to use for personal purposes, and the majority of them can also be used for commercial purposes. It’s a fun place to go for design news and inspiration. Being such a large vector community, Vecteezy offers a wide range of materials organized into categories such as Backgrounds, Icons, Elements, and banners.į is a website where you can get free vectors, icons, wallpapers, and logos. is a website where artists from all over the globe submit millions of free vector designs. You can sign up Shutterstock for free for 1 month and free download Lunar New Year 2022 images, banners and more. All Shutterstock pictures are Royalty-Free, and all images purchased as part of a subscription or image pack have a Shutterstock Standard License. Shutterstock has a large library of photos and videos, as well as strong search features to help you find what you’re looking for. Shutterstock is a global leader in the licensing of high-quality pictures, videos, and music. There are thousands of The Year Of Tiger templates available on Canva that you can easily & freely edit them to meet your ideas. Canva is a free graphic design software and lets you modify photographs without having any prior expertise or understanding of photo editing. Freepik will enable you locate free vector art, drawings, icons, PSD files, and backgrounds for Lunar New Year 2022 to use in your websites and banners.Ĭanva is a powerful graphic design tool for making social media graphics, presentations, posters, papers, and other visual material. It provides one of the most complete collections of free graphic materials (vectos, psd, photos & icons). Top 10 Free Graphic Material Resources for Lunar New Year 2022 1- Freepikį is the most popular website for graphic artists looking for vector graphics. These Chinese New Year banners, backgrounds and vector files are in PSD, PNG, EPS, and AI formats that you will simply edit them. To take it easy for you to find the ones you like, we have collected 10 best free Luna New Year banner, vector & background resources. There are millions of free banners, background and vectors for the Lunar New Year 2022 are available to download. To prepare for this special season, you might need some banners, vectors or Background to decorate your website, or creating greeting cards and party invitations. Lunar New Year 2022 is coming all around us. I quickly walked into a tiny dressing cubicle. It was decided that I would go change while she had a brief tour. I introduced my daughter and explained that she’d love to see the radiation room. In the hospital, after sitting down to wait for our turn, my name was called and for the first time, someone else got up and walked into the treatment area with me. The thing was, I needed someone to take me to the hospital, and she needed to feel needed. She said that this would give other people a break. I explained that she didn’t need to take me for my treatments and that I had rides lined up. When my daughter came home from university in the spring, she wanted to help. It was my secret, and that made it easier for me to feel as if my cancer wasn’t real. It was like dropping someone off at the mall. The appointments were quick, and they wouldn’t need to pay for parking if they stayed in the car, but also, and more importantly, I realize now that I could remain the same person I was before I got out of their car if they didn’t see me inside the hospital. When friends drove me to my appointments, I asked them to wait in the car. While the medical community treated the “out of control” in my body, I worked to remain in control.Īs a radiology patient, I only allowed two people to go into the hospital with me over the four weeks that I was a patient. It is created from atypical cells that duplicate out of control. Medically speaking though, cancer is abnormal. Wherever I went, however, I presented a perfect persona and pushed my cancer down further into my Jungian shadow. Should I have responded differently? And why didn’t I when he asked? It was my opportunity to connect. “Yes,” I replied, “Just tired.” He knowingly nodded and walked past me. It was normal I made it normal for everyone including myself.Ī colleague inquired if I was okay when I was moving up a double flight of stairs as slowly as a snail. Everything appeared normal when I returned to work after one week. Some of our most popular All Inclusive Honeymoons offer honeymoon suites with your own jacuzzi, or a Private all-inclusive honeymoon cottage with your own plunge pool like Hammock Cove Antigua. Hence, we gave it a thought and put the best of Vegas honeymoon ideas together in an absolute guide. One of our Favorite St Lucia all Inclusive Honeymoons, Calabash Cove Resort, offers an Oceanfront cottage with plunge pool on a secluded beach with high end personalized service. We have selected some of the most loved Caribbean, Mexico and Costa Rica All Inclusive Honeymoon resorts. 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We offer some of the worlds best Adult-Only All Inclusive Resorts perfect for couples seeking privacy and their own plunge pools. For that exclusive suite, definitely plan to pay 1,000+ per night. Élia Beach Club at Virgin Hotels Las Vegas is inspired by international beach destinations, with cabanas for lounging, a sand-bottom pool, and a shaded bar serving signature tropical cocktails. Unforgettable Honeymoons®, The Nation’s Leading Honeymoon Travel Experts since 1994 handpicked the Best All-Inclusive Honeymoon Packages and All Inclusive Honeymoon Resorts best for Romance, Value and Intimacy. Peruse Our Expert Handpicked All Inclusive Honeymoons Adults-Only Resorts, Private All Inclusive Pool Suites, Affordable All Inclusive Honeymoon Nevertheless, great advancements have recently been made towards addressing these two hurdles. However, due to the high false positive rate and the low detection sensitivity, the diagnostic potential of these discoveries has not been fully realized in a clinical setting. Using bulk RNAseq, numerous novel gene fusions have been discovered, many of which can be directly beneficial as FDA approved drugs or offer new therapeutic opportunities 14, 15, 16, 17. Some recurrent fusion genes can be used as a diagnostic tool, such as the RUNX1–RUNX1T1 fusion for diagnosis of acute myeloid leukemia 12, while others may be considered as prognostic biomarkers like TMPRSS2–ERG fusion in prostate cancer 13. Fusion genes are well documented as major cancer drivers. If this selection strategy is applicable in other tumor types, more biomarker signatures can be readily translated into clinical practice.Īnother area subject to intensive clinical research is gene fusion discoveries. Such a transcriptomic signature minimizes sampling bias and offers robust prognostic performance in NSCLC survival. These genes “encode expression modules of cancer cell proliferation and are often driven by DNA copy-number gains” 11. By analyzing multiple RNAseq data from lung cancer patients, the team found that genes with homogeneous expression within individual tumors, despite high inter tumor variability, have significantly better prognostic potential. A recent study provided a promising solution to tackle this issue through a novel strategy for biomarker selection 11. One of the main reasons for the poor performance across independent tumor patients is sampling bias inherent to intra-tumor heterogeneity 10. However, only a few such signature panels have been successfully translated into clinical practice due to low reproducibility. Numerous RNAseq-based signatures have been developed and validated across many major tumor types 5, 6, 7, 8, 9. The most informative area is the biomarker discoveries for cancer diagnosis, prognosis, and prediction. The translational research targeted for clinical oncology is primarily in two areas. 1).īulk RNAseq has broad utilities in cancer classification, biomarker and gene fusion discoveries, disease diagnosis, and optimizing therapeutic treatment. This type of bulk RNAseq normally sequences rRNA-depleted libraries for more comprehensive information (Fig. The less routinely used type is paired end longer sequencing aimed at additional knowledge on alternative splicing, point mutations, novel transcripts, long non-coding RNAs and gene fusions. This type of sequencing is simple and cost effective, largely focused on mRNA only. By sequencing type, the most frequently used bulk RNAseq is a single end short sequencing focused on differentially expressed genes to understand molecular mechanisms implicated in various stage of tumorigenesis. Instead, we will highlight the bottlenecks of its clinical translation and the recent progresses toward their solutions.īy RNA species, bulk RNAseq involves sequencing two types of libraries: mRNA-only library and whole transcriptome library that includes all RNA species except for rRNA. This section does not intend to discuss either technologies or its applications in details. Its diverse translational research and potential clinical applications have been well reviewed in the past 2, 3, 4. Since the first EST library was sequenced using Roche 454 sequencer in 2007 1, bulk RNAseq has become the most valuable and extensively used tool in understanding cancer biology. Therefore, RNAseq is a powerful tool for understanding the molecular mechanisms of cancer development and developing novel strategies for cancer prevention and treatment. Different gene expression profiles may reflect different cancer subtypes, the stage of cancer development or tumor microenvironment 2, 3, 4. Aberrant activation of cell growth signaling pathways and/or transcription factors could lead to high-level expression of genes associated with tumor development and progression. In addition to the mutation of tumor suppressor genes and oncogenes, gene expression could be overactivated or epigenetically silenced which could lead to uncontrolled tumor cell growth and proliferation. Abnormal expression of RNA is frequently associated with human cancer initiation, development, progression and metastasis. RNA transcription and stability are tightly regulated in response to physiological and pathological stimuli 1. Ribonucleic acid (RNA) has multiple forms and plays a critical role in cell growth and differentiation. Rerun the installer the same way as before.Īfer the installation completes, VirtualBox will be in your “Applications” folder. Then click “Allow” next to the message that software from “Oracle America, Inc.” was blocked. If you see “The installation failed” screen, then the installer was blocked.Ĭlick on the apple logo in the top left and click “System Preferences”Ĭlick the “Security & and Privacy” optionĬlick the padlock icon to allow you to make changes. When prompted with an authentication screen, enter the username and password for your user and click “Install Software” You can change where you want VirtualBox installed, or leave the default option and click “Install” When you see a prompt like below, click “Continue” You will see a screen like this:ĭouble click on “VirtualBox.pkg” to start the installer dmg file should be downloaded to your “Downloads” folder. Go to VirtualBox’s download page and click “OS X hosts”. VirtualBox runs on Windows, macOS, and Linux, and supports a wide array of guest operating systems. Oracle VM VirtualBox is a free application that allows you to run virtual machines (VMs) on your computer through software-based and hardware-assisted x86 virtualization. Please see the workaround at the end of this guide. In this screen, type 100GB and hit Create. Then set up 50 60 of your system’s memory and select Create a virtual hard disk now for the hard disk and click Create. There is a known problem installing VirtualBox on macOS High Siera. Now enter macOS Catalina for the name and specify a place to store the machine files. If you need to run VirtualBox VMs for classwork, you can use VirtualBox in our labs or install it on your own computer. Once the installation finishes, restart VirtualBox to access all of its features. Follow the on-screen instructions to complete the installation process. Select the extension pack, then choose Install. How to edit, compile, and run Java programs Then go to File > Preferences > Extensions > Add a new package.How to edit, compile, and run C++ programs.Remote file transfer on a Mac using Cyberduck.Remote file transfer on Windows using WinSCP.Remote file transfer on Linux/Mac systems.VirtualBox is a community effort backed by a dedicated company: everyone is encouraged to contribute while Oracle ensures the product always meets professional quality criteria. VirtualBox is being actively developed with frequent releases and has an ever growing list of features, supported guest operating systems and platforms it runs on. Presently, VirtualBox runs on Windows, Linux, macOS, and Solaris hosts and supports a large number of guest operating systems including but not limited to Windows (NT 4.0, 2000, XP, Server 2003, Vista, 7, 8, Windows 10 and Windows 11), DOS/Windows 3.x, Linux (2.4, 2.6, 3.x, 4.x, 5.x and 6.x), Solaris and OpenSolaris, OS/2, OpenBSD, NetBSD and FreeBSD. Open the Launchpad, type terminal, and select Terminal. See " About VirtualBox" for an introduction. You'll need the installer to install the latest version of macOS on a virtual. Wait for the virtual machine to start from the. Once you’ve done all the setup to install the Mac OS on VirtualBox, start the virtual PC and complete the installation, just like you would on an honest Mac. Not only is VirtualBox an extremely feature rich, high performance product for enterprise customers, it is also the only professional solution that is freely available as Open Source Software under the terms of the GNU General Public License (GPL) version 3. Once you’ve set up everything for the macOS VM using VirtualBox, start it for the installation. VirtualBox is a powerful x86 and AMD64/Intel64 virtualization product for enterprise as well as home use. VM VirtualBox, its high performance, cross-platform virtualization software. If its this one: brunomoreno89 wrote: Im using MacBook Air M1. Much more description is needed, and please start your own new topic. Oracle today released a significant new version of Oracle Which issue If its this one: Mac0s wrote: Cant Install Virtualbox 6.1.30 on macOS Monterey. Download the OVA file using the button above. Oracle today released a 6.1 maintenance release which improves stability and fixes regressions. VirtualBox image includes the Plasma Desktop (was KDE) as well as the VirtualBox guest additions. Oracle today released a 7.0 maintenance release which improves stability and fixes regressions. Whether a game has a Mac version or not becomes irrelevant with a cloud service subscription. You do need a stable Internet for the steam but the requirements are pretty low: 15 Mbps for Boosteroid and 20 Mbps for XCloud.įirst off, cloud gaming is a boon for those looking to dive into a wider array of games, beyond just Football Manager 2024. These services work by streaming games from a remote server, thereby offer a versatile way to experience a variety of games on your Mac, including those not natively available for macOS. Playing Football Manager 2024 on Mac with Cloud Gaming – is it worth it?Īlthough the Football Manager 2024 Steam version is compatible with Mac and the game is also available in the Mac App Store, there are still valid reasons to explore cloud gaming platforms like Boosteroid and Xbox Cloud Gaming. Enjoy managing your football team!Ī user on Reddit sharing their experience with FM24 on Mac.
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